From ZotGPT to Agentic AI: Tom Andriola’s Blueprint for Enterprise AI Leadership | CAIO Connect
In this episode of CAIO Connect, host Sanjay Puri sits down with Tom Andriola, former Vice Chancellor and Chief Digital Officer at UC Irvine and now at Dynatrace, to explore how universities and enterprises can scale AI responsibly. Tom—who led UC Irvine’s pioneering ZotGPT initiative—shares how he built one of the first university AI platforms in the U.S., branded business transformation, and prepared students for careers in the Age of AI. From agentic AI to the evolving role of the Chief AI Officer, this is a must-listen masterclass for leaders driving enterprise AI strategy.
5 Key Takeaways:
· Branding Transformation: Why business transformation initiatives should be branded like products to drive engagement and adoption.
· AI as a Coworker: How to build accountability and governance models for “silicon-based workers.”
· ROI & Outcomes: How to measure AI success through organisational outcomes—not just technical metrics.
· Edge, Leverage, and Trust: A framework for balancing central innovation with decentralised experimentation.
· The CAIO Mindset: Why Chief AI Officers must be bridge builders, translators, and transformation leaders—not just technologists.
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Resources Mentioned:
https://www.linkedin.com/in/tomandriola/






